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  • 產品名稱：ATCC8688a坎寧安菌Cunninghamella標準菌株菌種

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簡單介紹：
ATCC8688a坎寧安菌Cunninghamella標準菌株菌種
詳情介紹：
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出品公司:ATCC
_菌_種名稱:ATCC8688a, ATCC 8688a
_菌_種又名:NRRL 1369 [DSM 1906, IMI 53585, IMI 63877]
_菌_株類型:坎寧安_菌_Cunninghamella
存儲人:NRRL
分離來源: 
產品目錄號:8688a
其他保藏庫編號:BCRC30529,ATCC 8688a; DSM 1906; IMI 53585; IMI 63877; NRRL 1369
培養(yǎng)基:ATCC® Medium 200: YM agar or YM brothATCC® Medium 307: Cornmeal agarATCC® Medium 336: Potato dextrose agar (PDA)
生長條件:24-26℃,  有氧
生物安_全等級:1
模式_菌_株:否
應用:科研，生產，主要用于氧化依巴斯汀,產生1’，2’-二氫-1’，2’-二羥基魚藤酮,產生1,2-二氫魚藤酮,產生3’-羥基魚藤酮,產生肌鈣蛋白,生產丙咪嗪,轉化生物堿,轉化類黃酮,轉換藤架,依巴斯汀氧化為卡巴斯汀,倍半萜內酯-科斯圖內酯的轉化,藤架改為藤架亞砜
_菌_株特點:坎寧安_菌_Cunninghamella
參考文獻:Sariaslani FS, Rosazza JP. Microbial transformations of natural antitumor agents: Products of rotenone and dihydrorotenone transformation by Cunninghamella blakesleeana. Appl. Environ. Microbiol. 45: 616-621, 1983. Ibrahim AR, Abul-Hajj YJ. Microbiological transformation of flavone and isoflavone. Xenobiotica 20: 363-373, 1990. PubMed: 2346033 Mann KM, et al. Studies on microbiological oxidation of steroids by Cunninghamella blakesleeana. Effect of alcohols and phenol. Appl Microbiol 3: 14, 1955. Schwartz H, et al. Microbial oxidation of ebastine. Appl. Microbiol. Biotechnol. 44: 731-735, 1996. PubMed: 8867630 Betts RE, et al. Microbial transformations of antitumor compounds. I. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata. J. Med. Chem. 17: 599-602, 1974. PubMed: 4829940 Clark AM, Hufford CD. Microbial transformations of the sesquiterpene lactone costunolide. J. Chem. Soc. Perkin Trans. 1979: 3022-3028, 1979. Hufford CD, et al. Metabolism of imipramine by microorganisms. J. Pharm. Sci. 70: 151-155, 1981. PubMed: 7205217 Reighard JB, et al. Microbial biotransformations. I. O-Demethylation of 7,8-dimethoxy-2-methyl-1-(4'-methoxybenzyl) 1,2,3,4.-tetrahydroisoquinoline by Cunninghamella blakesleeana. J. Nat. Prod. 44: 466-469, 1981. Smith RV, et al. Microbial transformations of pergolide to pergolide sulfoxide and pergolide sulfone. J. Pharm. Sci. 72: 733-736, 1983. PubMed: 6684155

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