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產(chǎn)品詳情

  • 產(chǎn)品名稱：2'-5'-Oligoadenylate Synthetase 1 (OAS1) Antibody

  • 產(chǎn)品型號：abx032742
  • 產(chǎn)品廠商：abbexa
  • 產(chǎn)品文檔：
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簡單介紹：
2'-5'-Oligoadenylate Synthetase 1 (OAS1) Antibody
詳情介紹：
OAS1 is an interferon inducible protein that may play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis. It binds double-stranded RNA and polymerizes ATP into PPP (A2'P5'A) N oligomers, which activate the latent RNase L that, when activated, cleaves single-stranded RNAs. This protein is associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.

Target 2'-5'-Oligoadenylate Synthetase 1 (OAS1)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 302-330 amino acids from the C-terminal region of human OAS1.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P00973 (UniProt, ExPASy)
UniProt Entry Name OAS1_HUMAN
NCBI Accession NP_001027581.1 NP_002525.2 NP_058132.2
KEGG hsa:4938
String 9606.ENSP00000388001
Molecular Weight Calculated MW: 46 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 2'-5'-Oligoadenylate Synthetase 1 (OAS1)
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