產(chǎn)品詳情
簡單介紹：
Anti-FRAT1 antibody (70-170) [S4163RM] (STJ11104163)
詳情介紹：
| Host: | Rabbit |
| Applications: | IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit monoclonal antibody anti-Proto-Oncogene Frat1 (70-170) is suitable for use in Immunofluorescence research applications. |
| Clonality: | Monoclonal |
| Clone ID: | S4163RM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | IF/ICC 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FRAT1 |
| Gene ID: | 10023 |
| Uniprot ID: | FRAT1_HUMAN |
| Immunogen Region: | 70-170 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-170 of human FRAT1 (NP_005470.2). |
| Immunogen Sequence: | PLRAPGPLAAAVPADKARSP AVPLLLPPALAETVGPAPPG VLRCALGDRGRVRGRAAPYC VAELATGPSALSPLPPQADL DGPPGAGKQGIPQPLSGPCR R |
| Post Translational Modifications | Phosphorylated. |
| Function | Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis. |
| Protein Name | Proto-Oncogene Frat1 Frequently Rearranged In Advanced T-Cell Lymphomas 1 Frat-1 |
| Database Links | Reactome: R-HSA-196299 Reactome: R-HSA-4641262 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Proto-Oncogene Frat1 antibody Anti-Frequently Rearranged In Advanced T-Cell Lymphomas 1 antibody Anti-Frat-1 antibody Anti-FRAT1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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