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產(chǎn)品詳情

  • 產(chǎn)品名稱：Anti-SLC6A1 antibody (500-600) (STJ110041)

  • 產(chǎn)品型號(hào)：STJ110041
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Anti-SLC6A1 antibody (500-600) (STJ110041)
詳情介紹：
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-SLC6A1 (500-600) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: SLC6A1
Gene ID: 6529
Uniprot ID: SC6A1_HUMAN
Immunogen Region: 500-600
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 500-600 of human SLC6A1 (P30531).
Immunogen Sequence: WSFFTPIIVAGVFIFSAVQM TPLTMGNYVFPKWGQGVGWL MALSSMVLIPGYMAYMFLTL KGSLKQRIQVMVQPSEDIVR PENGPEQPQAGSSTSKEAYI
Function Mediates transport of gamma-aminobutyric acid (GABA) together with sodium and chloride and is responsible for the reuptake of GABA from the synapse. The translocation of GABA, however, may also occur in the reverse direction leading to the release of GABA. The direction and magnitude of GABA transport is a consequence of the prevailing thermodynamic conditions, determined by membrane potential and the intracellular and extracellular concentrations of Na(+), Cl(-) and GABA. Can also mediate sodium- and chloride-dependent transport of hypotaurine but to a much lower extent as compared to GABA.
Protein Name Sodium- And Chloride-Dependent Gaba Transporter 1
Gat-1
Solute Carrier Family 6 Member 1
Database Links Reactome: R-HSA-442660
Reactome: R-HSA-888593
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Presynapse
Localized At The Presynaptic Terminals Of Interneurons
Alternative Antibody Names Anti-Sodium- And Chloride-Dependent Gaba Transporter 1 antibody
Anti-Gat-1 antibody
Anti-Solute Carrier Family 6 Member 1 antibody
Anti-SLC6A1 antibody
Anti-GABATR antibody
Anti-GABT1 antibody
Anti-GAT1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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