產(chǎn)品詳情
簡單介紹：
Anti-CD45.2/Ptprc antibody [104.2] (STJA0001762)
詳情介紹：
| Host: | Mouse |
| Applications: | FC/IHC |
| Reactivity: | Mouse |
| Note: | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: | Mouse monoclonal antibody anti-Receptor-type tyrosine-protein phosphatase C is suitable for use in Flow Cytometry and Immunohistochemistry research applications. |
| Clonality: | Monoclonal |
| Clone ID: | 104.2 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2ak |
| Formulation: | PBS with 0.05% Proclin300 |
| Concentration: | 0.5 mg/mL |
| Storage Instruction: | Store at 2-8°C. Do not freeze this product. |
| Gene Symbol: | Ptprc |
| Gene ID: | 19264 |
| Uniprot ID: | PTPRC_MOUSE |
| Post Translational Modifications | Heavily N- and O-glycosylated. |
| Function | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. |
| Protein Name | Receptor-Type Tyrosine-Protein Phosphatase C Leukocyte Common Antigen L-Ca Lymphocyte Antigen 5 Ly-5 T200 Cd Antigen Cd45 |
| Database Links | Reactome: R-MMU-202427 Reactome: -MMU-416700 Reactome: -MMU-6798695 |
| Cellular Localisation | Cell Membrane Single-Pass Type I Membrane Protein Membrane Raft Colocalized With Dpp4 In Membrane Rafts |
| Alternative Antibody Names | Anti-Receptor-Type Tyrosine-Protein Phosphatase C antibody Anti-Leukocyte Common Antigen antibody Anti-L-Ca antibody Anti-Lymphocyte Antigen 5 antibody Anti-Ly-5 antibody Anti-T200 antibody Anti-Cd Antigen Cd45 antibody Anti-Ptprc antibody Anti-Ly-5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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