產(chǎn)品詳情
簡單介紹：
Anti-FGF13 antibody (1-245) (STJ110204)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-FGF13 (1-245) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FGF13 |
| Gene ID: | 2258 |
| Uniprot ID: | FGF13_HUMAN |
| Immunogen Region: | 1-245 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human FGF13 (NP_004105.1). |
| Immunogen Sequence: | MAAAIASSLIRQKRQARERE KSNACKCVSSPSKGKTSCDK NKLNVFSRVKLFGSKKRRRR RPEPQLKGIVTKLYSRQGYH LQLQADGTIDGTKDEDSTYT LFNLIPVGLRVVAIQGVQTK LYLAMNSEGYLYTSELFTPE CKFKESVFENYYVTYSSMIY RQQQSGRGWYLGLNKEGEIM KGNHVKKNKPAAHFLPKPLK VAMYKEPSLHDLTEFSRSGS GTPTKSRSVSGVLNGGKSM |
| Tissue Specificity | Ubiquitously expressed. Predominantly expressed in the nervous system. |
| Post Translational Modifications | May be phosphorylated. |
| Function | Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling. Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons. |
| Protein Name | Fibroblast Growth Factor 13 Fgf-13 Fibroblast Growth Factor Homologous Factor 2 Fhf-2 |
| Database Links | Reactome: R-HSA-5576892 |
| Cellular Localisation | Isoform 1: Nucleus Isoform 2: Cytoplasm Nucleus Isoform 3: Cytoplasm Isoform 4: Cytoplasm Isoform 5: Cytoplasm Cell Projection Filopodium Growth Cone Dendrite Cell Membrane Sarcolemma Cytoplasm Not Secreted Localizes To The Lateral Membrane And Intercalated Disks Of Myocytes |
| Alternative Antibody Names | Anti-Fibroblast Growth Factor 13 antibody Anti-Fgf-13 antibody Anti-Fibroblast Growth Factor Homologous Factor 2 antibody Anti-Fhf-2 antibody Anti-FGF13 antibody Anti-FHF2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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